We report a versatile ‘Trojan Horse’ strategy using highly anionic poly(methacrylic acid)–poly(benzyl methacrylate) vesicles to incorporate two types of model payloads, i.e. either silica nanoparticles or an organic dye (fluorescein), within CaCO₃ (calcite). Uniform occlusion of silica-loaded vesicles was confirmed by scanning electron microscopy, while thermogravimetry studies indicated extents of vesicle occlusion of up to 9.4% by mass (∼33% by volume). Efficient dye-loaded vesicle occlusion produces highly fluorescent calcite crystals as judged by fluorescence microscopy. In control experiments, silica nanoparticles alone are barely occluded, while only very weakly fluorescent calcite crystals are obtained when using just the fluorescein dye. This new ‘Trojan Horse’ strategy opens up a generic route for the efficient occlusion of various nanoparticles and organic molecules within inorganic host crystals.

中文翻译：

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阴离子嵌段共聚物囊泡充当特洛伊木马，能够有效地将客体物质封闭到主体方解石晶体中†

我们报告了一种多功能“特洛伊木马”策略，使用高阴离子聚（甲基丙烯酸）-聚（甲基丙烯酸苄酯）囊泡，将两种类型的模型有效负载（即二氧化硅纳米颗粒或有机染料（荧光素））合并到 CaCO 3 （方解石_）中。通过扫描电子显微镜证实了装载二氧化硅的囊泡的均匀闭塞，而热重分析研究表明囊泡闭塞程度高达 9.4%（按质量计）（约 33%（按体积计））。通过荧光显微镜判断，有效的负载染料的囊泡闭塞产生高荧光方解石晶体。在对照实验中，单独的二氧化硅纳米颗粒几乎不被吸留，而当仅使用荧光素染料时，仅获得非常弱的荧光方解石晶体。这种新的“特洛伊木马”策略开辟了一条在无机基质晶体内有效封闭各种纳米颗粒和有机分子的通用途径。