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The Horizon of the Emulsion Particulate Strategy: Engineering Hollow Particles for Biomedical Applications.
Advanced Materials ( IF 27.4 ) Pub Date : 2018-09-09 , DOI: 10.1002/adma.201801159
Yufei Xia 1, 2 , Xiangming Na 1, 2 , Jie Wu 1, 3 , Guanghui Ma 1, 3, 4
Affiliation  

With their hierarchical structures and the substantial surface areas, hollow particles have gained immense research interest in biomedical applications. For scalable fabrications, emulsion-based approaches have emerged as facile and versatile strategies. Here, the recent achievements in this field are unfolded via an "emulsion particulate strategy," which addresses the inherent relationship between the process control and the bioactive structures. As such, the interior architectures are manipulated by harnessing the intermediate state during the emulsion revolution (intrinsic strategy), whereas the external structures are dictated by tailoring the building blocks and solidification procedures of the Pickering emulsion (extrinsic strategy). Through integration of the intrinsic and extrinsic emulsion particulate strategy, multifunctional hollow particles demonstrate marked momentum for label-free multiplex detections, stimuli-responsive therapies, and stem cell therapies.

中文翻译:

乳液微粒化策略的视野:生物医学应用的工程空心颗粒。

空心颗粒凭借其层次结构和较大的表面积,已在生物医学应用中获得了巨大的研究兴趣。对于可扩展的制造,基于乳液的方法已经成为一种简便而通用的策略。在此,通过“乳液颗粒策略”展现了该领域的最新成就,该策略解决了过程控制与生物活性结构之间的内在联系。这样,通过利用乳液旋转过程中的中间状态来控制内部结构(内部策略),而外部结构则是通过调整Pickering乳液的结构单元和固化程序(外部策略)来决定的。通过整合内在和外在乳液颗粒策略,
更新日期:2018-09-09
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