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Insecticide Exposure and Development of Nonalcoholic Fatty Liver Disease
Journal of Agricultural and Food Chemistry ( IF 5.7 ) Pub Date : 2018-09-07 00:00:00 , DOI: 10.1021/acs.jafc.8b03177 Jason S. Yang 1 , Yeonhwa Park 1
Journal of Agricultural and Food Chemistry ( IF 5.7 ) Pub Date : 2018-09-07 00:00:00 , DOI: 10.1021/acs.jafc.8b03177 Jason S. Yang 1 , Yeonhwa Park 1
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Nonalcoholic fatty liver disease (NAFLD) is the prevalent liver disease resulting from metabolic disorder, which is highly associated with obesity and type 2 diabetes. Emerging evidence has shown that insecticide exposure disrupts lipid and glucose metabolism and results in obesity and type 2 diabetes. However, the potential impact of insecticide exposure on the liver functions related to NAFLD development is largely unknown. Thus, this perspective focused on the current knowledge of the effect of insecticides on the liver functions, particularly lipid and glucose metabolism, as well as other liver functions to correlate insecticide exposure and the development of NAFLD.
中文翻译：
杀虫剂的暴露与非酒精性脂肪性肝病的发展
非酒精性脂肪性肝病（NAFLD）是由代谢异常导致的普遍性肝病，其与肥胖症和2型糖尿病高度相关。新兴证据表明，接触杀虫剂会破坏脂质和葡萄糖的代谢，并导致肥胖和2型糖尿病。但是，杀虫剂暴露对与NAFLD发育相关的肝功能的潜在影响在很大程度上尚不清楚。因此，该观点集中在杀虫剂对肝脏功能（尤其是脂质和葡萄糖代谢）以及其他与杀虫剂暴露和NAFLD发生相关的肝功能的影响的当前知识上。
更新日期：2018-09-07
中文翻译：
杀虫剂的暴露与非酒精性脂肪性肝病的发展
非酒精性脂肪性肝病（NAFLD）是由代谢异常导致的普遍性肝病，其与肥胖症和2型糖尿病高度相关。新兴证据表明，接触杀虫剂会破坏脂质和葡萄糖的代谢，并导致肥胖和2型糖尿病。但是，杀虫剂暴露对与NAFLD发育相关的肝功能的潜在影响在很大程度上尚不清楚。因此，该观点集中在杀虫剂对肝脏功能（尤其是脂质和葡萄糖代谢）以及其他与杀虫剂暴露和NAFLD发生相关的肝功能的影响的当前知识上。
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