Eight new iridal-type triterpenoid derivatives, including two noriridals with ether bridge (1–2); two iridals lactone (3–4), four monocyclic iridals (5–8), together with five known iridals (9–14) were identified from the rhizome of Belamcanda chinensis. Their structures were elucidated on the basis of comprehensive spectroscopic methods and electronic circular dichroism (ECD) calculations. Bioassay results showed that belamcanoxide B (1) exhibited moderated cytotoxic activities against HCT-116 and MCF-7 cell lines with IC₅₀ values of 5.58 and 3.35 μM.

中文翻译：

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从细胞活动的新iridal型三萜类衍生物，射干

八个新iridal型三萜类化合物的衍生物，其中包括两个noriridals用醚桥（1 - 2）; 2个iridals内酯（3 - 4），四个单环iridals（5 - 8），加上5个已知iridals（9 - 14）从根茎识别射干。在综合光谱法和电子圆二色性（ECD）计算的基础上阐明了它们的结构。生物测定结果表明，belamcanoxide B（1）对HCT-116和MCF-7细胞系表现出中等的细胞毒活性，IC ₅₀值为5.58和3.35μM。