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Covalent organic nanosheets for bioimaging†
Chemical Science ( IF 7.6 ) Pub Date : 2018-09-03 00:00:00 , DOI: 10.1039/c8sc02842g
Gobinda Das 1 , Farah Benyettou 1 , Sudhir Kumar Sharma , Sudhir Kumar Sharama 2 , Thirumurugan Prakasam 1 , Felipe Gándara 3 , Victor A de la Peña-O'Shea 4 , Na'il Saleh 5 , Renu Pasricha 1 , Ramesh Jagannathan 2 , Mark A Olson 6 , Ali Trabolsi 1
Affiliation  

Covalent organic nanosheets (CONs) have attracted much attention because of their excellent physical, chemical, electronic, and optical properties. Although covalent organic nanosheets have widely been used in many applications, there are only a few CONs that have been tested for bio-medical applications. Nanometer sized triazine-based nanosheets were obtained by exfoliating their bulk counterparts in water. The obtained nanosheets were dispersible and stable in water with enhanced photoluminescence properties compared to the bulk material. The nanosheets were biocompatible and non-toxic and showed ability to stain HeLa cell nuclei without additional assistance of an external targeting agent.

中文翻译:


用于生物成像的共价有机纳米片†



共价有机纳米片(CON)因其优异的物理、化学、电子和光学性能而备受关注。尽管共价有机纳米片已广泛应用于许多应用中,但只有少数 CON 经过生物医学应用测试。纳米尺寸的三嗪基纳米片是通过在水中剥离其块状对应物而获得的。所获得的纳米片在水中可分散且稳定,与块体材料相比,具有增强的光致发光性能。纳米片具有生物相容性和无毒性,并且能够在不需要外部靶向剂的额外帮助的情况下对 HeLa 细胞核进行染色。
更新日期:2018-09-03
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