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Imaging, myeloid precursor immortalization, and genome editing for defining mechanisms of leukocyte recruitment in vivo
Theranostics ( IF 12.4 ) Pub Date : 2018-03-23 , DOI: 10.7150/thno.23632
Sandra Gran , Lisa Honold , Olesja Fehler , Stefanie Zenker , Sarah Eligehausen , Michael T. Kuhlmann , Edwin Geven , Martijn van den Bosch , Peter van Lent , Christoph Spiekermann , Sven Hermann , Thomas Vogl , Michael Schäfers , Johannes Roth

Recruitment of leukocytes from the blood to sites of inflammation poses a promising target for new diagnostic and therapeutic approaches. We aimed to develop a novel method to non-invasively analyze molecular mechanisms of leukocyte migration in pre-clinical models of inflammation in vivo.

中文翻译:

成像,髓样前体永生化和基因组编辑,用于定义体内白细胞募集的机制

从血液到炎症部位的白细胞募集为新的诊断和治疗方法提出了有希望的目标。我们旨在开发一种新方法,以非侵入性方式分析体内炎症前临床模型中白细胞迁移的分子机制。
更新日期:2018-09-01
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