In this study, the electroactive hybrid gels with controllable sol-gel process were fabricated based on the water soluble polyaniline complex and water soluble silica precursor. β-cyclodextrin grafted on chitosan (CSCD) acted as a template, a new route for the synthesis of water soluble polyaniline complex (PA@CSCD) was designed by in-situ polymerization. Then, the hybrid silica gels without severe shrinkage were prepared by mixing PA@CSCD complex with water soluble precursor (tetrakis(2-hydroxyethyl)orthosilicates, THEOS). By dynamic rheological measurements, it was found that PA@CSCD complex could trigger and accelerate the sol-gel transition of the silica precursor. The gelation time could be largely shortened with the increase of PA@CSCD complex amount. By SEM observation, the PA@CSCD complex could be well compatible with the silica matrix. Moreover, the hybrid gels showed the good redox electroactivity, which could be successfully applied in a HRP-based biosensor.

在这项研究中，基于水溶性聚苯胺配合物和水溶性二氧化硅前体制备了具有可控溶胶-凝胶过程的电活性杂化凝胶。以壳聚糖（CSCD）上接枝的β-环糊精为模板，通过原位聚合设计了一种水溶性聚苯胺复合物（PA @ CSCD）的合成新途径。然后，通过将PA @ CSCD配合物与水溶性前体（原硅酸四（2-羟乙基）酯，THEOS）混合，制得没有严重收缩的杂化硅胶。通过动态流变学测量，发现PA @ CSCD配合物可以触发并加速二氧化硅前体的溶胶-凝胶转变。随着PA @ CSCD配合物量的增加，胶凝时间可大大缩短。通过SEM观察，PA @ CSCD配合物可以与二氧化硅基质很好地相容。