In particular industrial sectors, such as the cosmetic, there is a considerable amount of heuristics during the formulation stage, namely regarding qualitative function of ingredients, their incompatibilities, synergies and antagonisms, as well as their impact on sensorial attributes. In this work, the heuristic knowledge around the formulation of cosmetics emulsions has been incorporated into a systematic CAMD methodology. The methodology was tested in the creation of rinse-off hair conditioners. From an initial list of ingredients (i.e. twenty-four emollients, six thickeners and five emulsifiers) and a set of heuristics for their incorporation into cosmetic formulations, a group of optimized alternatives under specific performance and economic targets was obtained. Nine of the resulting formulations were prepared and then analyzed using instrumental methods. The rheological, textural and microstructural characteristics were similar for most of the samples, confirming the potential of this proposed methodology in designing and tailoring formulated products.

在特定的工业部门（例如化妆品）中，在配制阶段存在大量启发式的尝试，即有关成分的定性功能，其不相容性，协同作用和拮抗作用以及它们对感觉属性的影响。在这项工作中，有关化妆品乳液配方的启发式知识已被纳入系统的CAMD方法论中。该方法在冲洗型护发素的创建中进行了测试。从最初的成分清单（即二十四种润肤剂，六种增稠剂和五种乳化剂）以及将其掺入化妆品配方中的启发式方法，获得了在特定性能和经济目标下的一组优化替代品。制备了九种所得制剂，然后使用仪器方法进行了分析。大多数样品的流变，组织和微观结构特征均相似，证实了该方法在设计和定制配方产品中的潜力。