Sustainable organophosphorus-catalysed Staudinger reduction,Green Chemistry

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Sustainable organophosphorus-catalysed Staudinger reduction
Green Chemistry ( IF 9.3 ) Pub Date : 2018-08-29 , DOI: 10.1039/c8gc02136h
Danny C. Lenstra _{1,

2,

3,

4} , Peter E. Lenting _{1,

2,

3,

4} , Jasmin Mecinović _{1,

2,

3,

4}

Affiliation

A highly efficient and sustainable catalytic Staudinger reduction for the conversion of organic azides to amines in excellent yields has been developed. The reaction displays excellent functional group tolerance to functionalities that are otherwise prone to reduction, such as sulfones, esters, amides, ketones, nitriles, alkenes, and benzyl ethers. The green nature of the reaction is exemplified by the use of PMHS, CPME, and a lack of column chromatography.

中文翻译：

可持续的有机磷催化施陶丁格还原

已经开发出一种高效且可持续的Staudinger催化还原方法，用于以优异的产率将有机叠氮化物转化为胺。该反应对优异的官能团具有极好的官能团耐受性，这些官能团否则容易还原，例如砜，酯，酰胺，酮，腈，烯烃和苄基醚。通过使用PMHS，CPME和缺少柱色谱法可以举例说明反应的绿色性质。

更新日期：2018-10-01

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