Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management,Chemical Society Reviews

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Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management
Chemical Society Reviews ( IF 40.4 ) Pub Date : 2018-08-28 00:00:00 , DOI: 10.1039/c7cs00554g
Verónica Almeida-Marrero _{1,

2,

3,

4} , Eveline van de Winckel _{1,

2,

3,

4} , Eduardo Anaya-Plaza _{1,

2,

3,

4} , Tomás Torres _{1,

2,

3,

4,

5} , Andrés de la Escosura _{1,

2,

3,

4,

5}

Affiliation

The development of photoactive and biocompatible nanomaterials is a current major challenge of materials science and nanotechnology, as they will contribute to promoting current and future biomedical applications. A growing strategy in this direction consists of using biologically inspired hybrid materials to maintain or even enhance the optical properties of chromophores and fluorophores in biological media. Within this area, porphyrinoids constitute the most important family of organic photosensitizers. The following extensive review will cover their incorporation into different kinds of photosensitizing biohybrid materials, as a fundamental research effort toward the management of light for biomedical use, including technologies such as photochemical internalization (PCI), photoimmunotherapy (PIT), and theranostic combinations of fluorescence imaging and photodynamic therapy (PDT) or photodynamic inactivation (PDI) of microorganisms.

中文翻译：

卟啉类生物混合材料作为生物医学光管理的新兴工具箱

光敏性和生物相容性纳米材料的开发是材料科学和纳米技术当前面临的主要挑战，因为它们将有助于促进当前和未来的生物医学应用。朝这个方向发展的策略包括使用受生物启发的杂化材料来维持或什至增强生物介质中发色团和荧光团的光学特性。在该区域内，卟啉类化合物是最重要的有机光敏剂家族。以下广泛审查将涵盖将它们掺入不同种类的光敏生物杂交材料中，作为针对生物医学用途光管理的基础研究工作，包括光化学内在化（PCI），光免疫疗法（PIT），

更新日期：2018-08-28

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