Abstract In-injection port thermal desorption (TD) was extended in determination of particulate phase nitrated-polycyclic aromatic hydrocarbons (N-PAHs) on filter samples coupled with a gas chromatography/negative ion chemical ionization-mass spectrometry (GC/NCI-MS). The experimental and analytical parameters were optimized with standard testing and ambient samples. Fourteen of the most abundant N-PAHs in ambient airs were included for their quantification. A desorption temperature of 280 °C for 10 min was sufficient to transfer entire target compounds from injection port to the analytical system. Good linearity (R2 >0.995) on the calibrations for each analyte was achieved. The limit of detections (LODs) ranged from 46.5 to 152.3 pg per filter sample, which were 4–66% better than solvent extraction (SE) approach. Method precision, repeatability and reproducibility, determined by replicate analyses of calibration standards and ambient samples, were less than 6% for target compounds. Validation of the method were conducted with two batches of a total of 30 ambient aerosol-loaded filters using our TD and the traditional SE approaches. Reasonably good agreement (R2 = 0.98) by the two methods was demonstrated for most of N-PAHs, except for 9-nitrophenanthrene and 6-nitrobenzo(a)pyrene. The in-injection port TD can improve laboratory efficiency and reduce solvent-based costs for the measurement of N-PAHs.

中文翻译：

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技术说明：使用进样口热脱附-气相色谱/负化学电离质谱法定量大气气溶胶样品中的硝化多环芳烃

摘要 进样口热解吸 (TD) 扩展用于结合气相色谱/负离子化学电离质谱 (GC/NCI-MS) 测定过滤器样品中的颗粒相硝化多环芳烃 (N-PAH) . 实验和分析参数通过标准测试和环境样品进行了优化。环境空气中 14 种最丰富的 N-PAHs 被纳入量化。280 °C 解吸温度 10 分钟足以将整个目标化合物从进样口转移到分析系统。每种分析物的校准都获得了良好的线性 (R2 > 0.995)。每个过滤器样品的检测限 (LOD) 范围为 46.5 至 152.3 pg，比溶剂萃取 (SE) 方法好 4-66%。方法精度，通过校准标准和环境样品的重复分析确定的目标化合物的重复性和再现性小于 6%。使用我们的 TD 和传统 SE 方法对两批共 30 个环境气溶胶负载过滤器进行了方法验证。除了 9-硝基菲和 6-硝基苯并 (a) 芘外，大多数 N-PAH 都证明了两种方法具有相当好的一致性 (R2 = 0.98)。进样口 TD 可以提高实验室效率并降低测量 N-PAH 的溶剂成本。使用我们的 TD 和传统 SE 方法对两批共 30 个环境气溶胶负载过滤器进行了方法验证。除了 9-硝基菲和 6-硝基苯并 (a) 芘外，大多数 N-PAH 都证明了两种方法具有相当好的一致性 (R2 = 0.98)。进样口 TD 可以提高实验室效率并降低测量 N-PAH 的溶剂成本。使用我们的 TD 和传统 SE 方法对两批共 30 个环境气溶胶负载过滤器进行了方法验证。除了 9-硝基菲和 6-硝基苯并 (a) 芘外，大多数 N-PAH 都证明了两种方法具有相当好的一致性 (R2 = 0.98)。进样口 TD 可以提高实验室效率并降低测量 N-PAH 的溶剂成本。