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Development of an Automated Continuous Clarification Bypass System To Remove Suspended Particulate Matter
Organic Process Research & Development ( IF 3.4 ) Pub Date : 2018-08-28 00:00:00 , DOI: 10.1021/acs.oprd.8b00195
Wei Wu 1 , Matthew G. Lesher 1 , Chuntian Hu 1 , Khrystyna Shvedova 1 , Bayan Takizawa 1 , Thomas F. O’Connor 2 , Xiaochuan Yang 2 , Sukumar Ramanujam 3 , Salvatore Mascia 1
Affiliation  

An automated continuous clarification bypass system was developed to remove the suspended particulate matter (SPM) in the prereaction material. Compared to commercially available duty/standby filters, the proposed clarification bypass system is able to self-clean and does not require detachment of the filter and manual cleaning. In a stainless steel (SS) filter, the effects of flow direction, ultrasonication, and viscosity (=f(temperature)) were investigated. The data showed that the filtration performance could not meet the requirement of high clarification efficiency because of the high switch frequency (high switch frequency results from short filtration time before the filter fouls, which is indicated by increasing pressure differential across the filter). The deposition of crystals on the SS filter medium, and not the SPM, was the primary cause of the pressure build-up. Experiments with PTFE filter elements with comparable pore size and surface area to the stainless-steel filter were performed, and improved filtration performance (e.g., after the first cycle, the filtering time was 1–3 min with SS versus 30–60 min with PTFE) was observed. At the beginning of the SPM filtration process with the PTFE filter elements, three filtration mechanisms occurred (i.e., straining, impingement, and entanglement). As the filtration cake formed on the filter element surface, straining gradually dominated the filtration process, while the effects of impingement and entanglement became negligible.

中文翻译:

开发自动连续澄清旁路系统以去除悬浮的颗粒物

开发了一种自动连续澄清旁路系统,以除去预反应材料中的悬浮颗粒物(SPM)。与市售的工作/备用过滤器相比,建议的澄清旁路系统能够自清洁,不需要拆卸过滤器和手动清洁。在不锈钢(SS)过滤器中,流向,超声处理和粘度(= f(温度))进行了研究。数据表明,由于开关频率高(高开关频率是由于过滤器结垢前过滤时间短而导致的,这是通过增加过滤器的压差来表明的),因此过滤性能无法满足高澄清效率的要求。晶体沉积在SS过滤介质上而不是SPM上是造成压力升高的主要原因。进行了具有与不锈钢过滤器相当的孔径和表面积的PTFE过滤器元件的实验,并改善了过滤性能(例如,在第一个循环之后,SS的过滤时间为1-3分钟,而PTFE的过滤时间为30-60分钟) 被观测到。在采用PTFE滤芯的SPM过滤过程开始时,发生了三种过滤机制(即, 紧张撞击纠缠)。随着滤饼在滤芯表面上形成,应变逐渐主导了过滤过程,而撞击缠结的影响可忽略不计。
更新日期:2018-08-28
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