In this review, we focus on recent advances in the synthesis of polymer‐functionalized transition‐metal‐based nanomaterials and follow this up by discussing their applications in bioimaging diagnosis and cancer therapy. Transition‐metal‐based nanomaterials show great potential in cancer therapy owing to their intensive near‐IR absorption, excellent photothermal conversion efficiency, strong X‐ray attenuation, and magnetic properties. Functional polymers are usually introduced by a one‐step or multistep method to further endow these nanomaterials with great biocompatibility and physiological stability. Polymer‐decorated transition‐metal nanomaterials show great potential in multimodal imaging diagnosis (photoacoustic imaging, computed tomography, photoluminescence imaging, positron emission tomography, etc.) and cancer therapy (chemotherapy, photothermal therapy, microwave therapy, radiotherapy, photodynamic therapy). At the end of this review, the prospects of these polymer‐decorated transition‐metal‐based nanomaterials are also discussed.

中文翻译：

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功能性聚合物修饰的过渡金属纳米材料在生物成像和癌症治疗中的最新进展

在这篇综述中，我们关注于聚合物功能化过渡金属基纳米材料合成的最新进展，并通过讨论其在生物成像诊断和癌症治疗中的应用来跟进。基于过渡金属的纳米材料由于其强大的近红外吸收，出色的光热转换效率，强大的X射线衰减和磁性能而在癌症治疗中显示出巨大的潜力。通常通过一步或多步方法引入功能聚合物，以进一步赋予这些纳米材料很大的生物相容性和生理稳定性。聚合物装饰的过渡金属纳米材料在多峰成像诊断（光声成像，计算机断层扫描，光致发光成像，正电子发射断层扫描等）和癌症治疗（化学疗法，光热疗法，微波疗法，放射疗法，光动力疗法）。在这篇评论的最后，还讨论了这些聚合物修饰的过渡金属基纳米材料的前景。