Front Cover: Responsive Fluorescence Probe for Selective and Sensitive Detection of Hypochlorous Acid in Live Cells and Animals (Chem. Asian J. 18/2018),Chemistry - An Asian Journal

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Front Cover: Responsive Fluorescence Probe for Selective and Sensitive Detection of Hypochlorous Acid in Live Cells and Animals (Chem. Asian J. 18/2018)
Chemistry - An Asian Journal ( IF 3.5 ) Pub Date : 2018-08-23 , DOI: 10.1002/asia.201801106
Huan Feng ₁ , Qingtao Meng ₁ , Yue Wang ₁ , Chengchen Duan ₂ , Cuiping Wang ₁ , Hongmin Jia ₁ , Zhiqiang Zhang ₁ , Run Zhang ₂

Affiliation

Being hyporesponsive: A new responsive fluorescence probe, PQI, is reported for quantitative fluorescence detection of hypochlorous acid (HOCl) in aqueous solution and live organisms. PQI features a large Stokes shift, high sensitivity and selectivity, and rapid fluorescence response towards HOCl. Quantitative detection of HOCl in single live cells was demonstrated through fluorescence imaging and flow cytometry analysis. In vivo sensing and imaging of HOCl in zebrafish and nude mice were achieved by using PQI as the fluorescence probe. More information can be found in the Full Paper by Qingtao Meng, Run Zhang et al. on page 2611 in Issue 18, 2018 (DOI: 10.1002/asia.201800957).

中文翻译：

封面：用于选择性和灵敏检测活细胞和动物中次氯酸的响应荧光探针（Chem.Asian J.18 / 2018）

低反应性：据报道，一种新型的反应性荧光探针PQI用于定量检测水溶液和活生物体中的次氯酸（HOCl）。PQI具有较大的斯托克斯位移，高灵敏度和选择性以及对HOCl的快速荧光响应。通过荧光成像和流式细胞术分析证明了在单个活细胞中HOCl的定量检测。斑马鱼和裸鼠体内HOCl的体内感测和成像是通过使用PQI作为荧光探针实现的。可以在孟庆涛，张润等人的论文全文中找到更多信息。就在第18期，2018页2611（：10.1002 / asia.201800957 DOI）。

更新日期：2018-08-23

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