In this study, TEMPO was efficiently grafted on MeOPEG support by copper-catalyzed (3 + 2) cycloaddition reaction. The newly immobilized MeOPEG-clicked TEMPO catalyst was characterized by NMR, IR, and MALDI-TOF. Subsequently, it was used for one-pot aerobic double dehydrogenation of alcohols to nitriles using aqueous ammonia as the nitrogen source and O₂ (1 atm) as the terminal oxidant. The catalytic efficiency was also reported with various benzyl, alkyl, and heteroaromatic alcohols. The reactivity of this catalyst is comparable with that of unmodified TEMPO. Furthermore, the new MeOPEG-clicked TEMPO catalyst could be easily recovered by precipitation and recycled up to five runs.

在这项研究中，通过铜催化的（3 + 2）环加成反应将TEMPO有效接枝到MeOPEG支持物上。通过NMR，IR和MALDI-TOF对新固定的MeOPEG单击的TEMPO催化剂进行了表征。随后，将其用于使用氨水作为氮源，以O ₂（1 atm）作为末端氧化剂的一锅好氧将酒精进行双氧脱氢成腈。还报道了使用各种苄基，烷基和杂芳族醇的催化效率。该催化剂的反应性与未改性的TEMPO相当。此外，新型MeOPEG单击的TEMPO催化剂可通过沉淀轻松回收，最多可循环运行五次。