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Recent Developments in Transition Metal‐Catalyzed Dearomative Cyclizations of Indoles as Dipolarophiles for the Construction of Indolines
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2018-10-18 , DOI: 10.1002/adsc.201800789
Guanghao Huang 1 , Biaolin Yin 1
Affiliation  

Fused polycyclic indoline skeletons are found in many natural products and bioactive molecules. Several approaches, including dearomative cyclization of functionalized indoles, have been developed for the rapid synthesis of these skeletons. As a result of extensive research over the past few decades, numerous elegant and efficient protocols for the transition metal‐catalyzed dearomative cyclization of indoles to afford indolines have been reported, and recent developments in this area are discussed in detail in this review.

中文翻译:

过渡金属催化的吲哚类化合物作为偶极亲和性吲哚类化合物的脱芳香环化反应的最新进展。

融合的多环吲哚啉骨架存在于许多天然产物和生物活性分子中。已经开发了几种方法,包括功能化吲哚的脱芳香环化,以快速合成这些骨架。在过去的几十年中,由于进行了广泛的研究,已经报道了许多用于过渡金属催化的吲哚脱芳香环化反应以生成二氢吲哚的优雅而有效的方案,本综述对此领域的最新进展进行了详细讨论。
更新日期:2018-10-18
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