Abstract A duplex coating composed of electrophoretic deposited graphene oxide (GO) inner-layer and electrodeposited GO/Mg substituted hydroxyapatite (MH) outer-layer was prepared on carbon/carbon composites (CC). The morphology and microstructure of GO-GO/MH coating were researched by Scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Raman spectroscopy and X-ray photoelectron spectroscopy. The bonding strength between GO-GO/MH coating and CC substrate was investigated by shear test. The in-vitro bioactivity of GO-GO/MH coating was analyzed by simulated body fluid (SBF) immersion test. The results demonstrated that electrophoretic deposited GO inner-layer was successfully introduced on CC and could serve as an interlayer between CC and following electrodeposited GO/MH outer-layer. GO/MH outer-layer presented a flake morphology with 150–250 nm in thickness and 1.5–2.5 µm in width, exhibiting porous three-dimensional networks structure uniformly. The shear test showed that the bonding strength between the duplex coating and CC reached 7.4 MPa, which was 80.49% higher than that of single-layered MH coating without GO. The duplex coating could induce the formation of flocculent and chapped apatite after SBF immersion, which demonstrated the in-vitro bioactivity of the duplex coating. These results suggested that GO-GO/MH coating might be a promising candidate in the field of biomaterials, especially for implant coatings.

中文翻译：

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用于生物医学应用的由电泳沉积氧化石墨烯内层和电沉积氧化石墨烯/镁取代羟基磷灰石外层组成的双涂层碳/碳复合材料

摘要 在碳/碳复合材料（CC）上制备了由电泳沉积氧化石墨烯（GO）内层和电沉积GO/Mg取代羟基磷灰石（MH）外层组成的双层涂层。通过扫描电子显微镜、能量色散X射线光谱、X射线衍射、拉曼光谱和X射线光电子能谱研究了GO-GO/MH涂层的形貌和微观结构。通过剪切试验研究了GO-GO/MH涂层与CC基材之间的结合强度。通过模拟体液（SBF）浸渍试验分析GO-GO/MH涂层的体外生物活性。结果表明，电泳沉积的 GO 内层成功地引入到 CC 上，并且可以作为 CC 和随后的电沉积 GO/MH 外层之间的夹层。GO/MH 外层呈片状形态，厚度为 150-250 nm，宽度为 1.5-2.5 µm，呈现均匀的多孔三维网络结构。剪切试验表明，双相涂层与CC的结合强度达到7.4 MPa，比不含GO的单层MH涂层高80.49%。双相涂层在SBF浸渍后可以诱导絮状和皲裂磷灰石的形成，这证明了双相涂层的体外生物活性。这些结果表明 GO-GO/MH 涂层可能是生物材料领域的一个有前途的候选材料，尤其是植入涂层。剪切试验表明，双相涂层与CC的结合强度达到7.4 MPa，比不含GO的单层MH涂层高80.49%。双相涂层在SBF浸渍后可以诱导絮状和皲裂磷灰石的形成，这证明了双相涂层的体外生物活性。这些结果表明 GO-GO/MH 涂层可能是生物材料领域的一个有前途的候选材料，尤其是植入涂层。剪切试验表明，双相涂层与CC的结合强度达到7.4 MPa，比不含GO的单层MH涂层高80.49%。在SBF浸渍后，双相涂层可以诱导絮状和皲裂磷灰石的形成，这证明了双相涂层的体外生物活性。这些结果表明 GO-GO/MH 涂层可能是生物材料领域的一个有前途的候选材料，尤其是植入涂层。