Bridging organic and inorganic chemistry as well as molecular biology, this undergraduate experiment deals with the synthesis of ligands for metal complexes that can cleave DNA. Students gain theoretical and experimental expertise about metal–DNA interactions and the mechanisms behind DNA cleavage. This experiment lays a basis for the understanding and the rational design of artificial DNA scissors and provides insight into interdisciplinary research in the field of bioinorganic chemistry.

中文翻译：

---

人工DNA剪刀的合成与评估：跨学科的本科生实验

在有机和无机化学以及分子生物学之间架起了一座桥梁，这项本科生实验致力于合成可以切割DNA的金属配合物的配体。学生将获得有关金属与DNA相互作用以及DNA裂解机制的理论和实验专业知识。该实验为理解和合理设计人造DNA剪刀奠定了基础，并为生物无机化学领域的跨学科研究提供了见识。