An atmospheric pressure interface transports ions from ambient pressure to the low-pressure environment of a mass spectrometer. A capillary coupled to an ion funnel is widely used. However, conventional ion funnels do little to negate the large amount of energy picked up by high-mass ions from the gas flow through the capillary. There has been little work done on the effects of gas flow on ion transmission, and the previous studies have all been limited to low-mass, low-charge ions. In this work, we account for the effects of gas flow, diffusion, and electric fields (static and oscillating) on ion trajectories and use simulations to design a new hybrid ion funnel-ion carpet (FUNPET) interface that transmits a broad mass range with a single set of instrument conditions. The design incorporates a virtual jet disruptor where pressure buildup and counter flow dissipate the supersonic jet that results from gas flow into the interface. This, and the small exit aperture that can be used with the FUNPET, reduces the gas flow into the next stage of differential pumping. The virtual jet disruptor thermalizes ions with a broad range of masses (1 kDa to 1 GDa), and once thermalized, they are transmitted into next region of the mass spectrometer with low excess kinetic energy. The FUNPET interface is easy to fabricate from flexible printed circuit board and a support frame made by 3D printing. The performance of the interface was evaluated using charge detection mass spectrometry.

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大气压界面将离子从环境压力传输到质谱仪的低压环境。与离子漏斗连接的毛细管被广泛使用。然而，常规的离子漏斗几乎不能抵消高质量离子从流过毛细管的气流中吸收的大量能量。关于气流对离子传输影响的研究很少，以前的研究都局限于低质量，低电荷的离子。在这项工作中，我们考虑了气体流动，扩散和电场（静态和振荡）对离子轨迹的影响，并使用模拟方法设计了一种新型的混合离子漏斗-离子地毯（FUNPET）界面，该界面可以传输较宽的质量范围。一套仪器条件。该设计包含一个虚拟的射流破坏器，在该射流破坏器中，由于气流进入界面而产生的压力积累和逆流消散了超音速射流。这以及可与FUNPET一起使用的小出口孔，减少了进入差动泵下一阶段的气体流量。虚拟喷射扰流器可对多种质量的离子（1 kDa至1 GDa）进行热化，一旦被热化，它们就会以较低的过剩动能被传输到质谱仪的下一个区域。FUNPET接口易于由柔性印刷电路板和3D打印制成的支撑框架制成。使用电荷检测质谱法评估界面的性能。以及可与FUNPET一起使用的小出口孔，减少了进入差动泵下一阶段的气体流量。虚拟喷射扰流器可对多种质量的离子（1 kDa至1 GDa）进行热化，一旦被热化，它们就会以较低的过剩动能被传输到质谱仪的下一个区域。FUNPET接口易于由柔性印刷电路板和3D打印制成的支撑框架制成。使用电荷检测质谱法评估界面的性能。以及可与FUNPET一起使用的小出口孔，减少了进入差动泵下一阶段的气体流量。虚拟喷射扰流器可对多种质量的离子（1 kDa至1 GDa）进行热化，一旦被热化，它们就会以较低的过剩动能被传输到质谱仪的下一个区域。FUNPET接口易于由柔性印刷电路板和3D打印制成的支撑框架制成。使用电荷检测质谱法评估界面的性能。FUNPET接口易于由柔性印刷电路板和3D打印制成的支撑框架制成。使用电荷检测质谱法评估界面的性能。FUNPET接口易于由柔性印刷电路板和3D打印制成的支撑框架制成。使用电荷检测质谱法评估界面的性能。

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