Anisotropic structures such as myofibrils, collagen, and elastic fibers are prevalent in tissues. The orientations of these anisotropic structures are important indicators in various biomedical studies. Here we analyze the ability of using Mueller matrix polar decomposition (MMPD) and Mueller matrix transformation (MMT) parameters to determine and distinguish the accurate orientations of different anisotropies originated from scattering and birefringence in backscattering measurements. The experimental results of complex phantoms and Monte Carlo simulations suggest that the MMT and MMPD parameters can be used to reveal the orientations of the cylindrical scatterers and birefringence in turbid media, respectively. Moreover, a preliminary application of these Mueller matrix-derived parameters on bovine tendon samples demonstrates the ability of using the parameters to distinguish anisotropic scattering and birefringence orientations of tissues. The anisotropy orientation information can be helpful for biomedical studies or diagnosis.

中文翻译：

---

使用Mueller矩阵导出的参数区分源自混浊介质的散射和双折射的各向异性取向

诸如肌原纤维，胶原蛋白和弹性纤维之类的各向异性结构在组织中普遍存在。这些各向异性结构的取向是各种生物医学研究中的重要指标。在这里，我们分析了使用Mueller矩阵极坐标分解（MMPD）和Mueller矩阵变换（MMT）参数来确定和区分源于反向散射测量中的散射和双折射的不同各向异性的准确方向的能力。复杂体模的实验结果和蒙特卡洛模拟表明，MMT和MMPD参数可分别用于揭示圆柱状散射体的方向和混浊介质中的双折射。而且，这些源自Mueller矩阵的参数在牛腱样品上的初步应用证明了使用这些参数区分组织的各向异性散射和双折射取向的能力。各向异性取向信息可用于生物医学研究或诊断。