Parkinson’s Disease (PD) is characterized by motor and non-motor symptoms such as cognitive deficit and behavioural disturbances. Apathy seems to be related to cognitive impairment, but some studies failed to confirm the relationship due to different methodological procedures across studies. A meta-analysis on 8 studies was performed to explore the cognitive correlates of apathy without depression and dementia (pure apathy). Global cognitive function, memory, executive functions, processing speed/attention/working memory, visuospatial abilities and language were the outcomes. The effect size of the relationship between “pure apathy” and reduced global cognitive functioning, executive functions, processing speed/attention/working memory, visuospatial functions, long-term verbal memory was moderate, whereas apathy was strongly associated with inhibition dysfunctioning.

Our results revealed a strong association between “pure apathy” and cognitive dysfunctions, particularly deficit of memory and executive functions related to altered prefronto-subcortical circuitries.

帕金森氏病（PD）的特征在于运动和非运动症状，例如认知缺陷和行为障碍。冷漠似乎与认知障碍有关，但由于各研究方法不同，一些研究未能证实这种关系。对8项研究进行了荟萃分析，以探讨无抑郁和痴呆（纯净冷漠）的冷漠与认知的相关性。结果是整体认知功能，记忆，执行功能，处理速度/注意力/工作记忆，视觉空间能力和语言。“纯粹的冷漠”与减少的整体认知功能，执行功能，处理速度/注意力/工作记忆，视觉空间功能，长期言语记忆之间的关系的影响大小是中等的，

我们的研究结果表明，“纯粹的冷漠”与认知功能障碍之间有很强的联系，特别是与前额皮质下皮层回路改变相关的记忆力和执行功能不足。