Quercetin (3,3',4',5,7-pentahydroxyflavone) is found in vegetables and fruits. It is one of the major flavonoids that is part of human diets. Quercetin has several pharmacological effects in the nervous system as a neuroprotective agent. In this review, we summarize the research on quercetin and its role in memory in both animals and humans. Articles were chosen from the Scopus, PubMed, and Web of Science databases. In this review, we describe and summarize the importance of quercetin's presence in the body, particularly in the brain; its kinetics, including its absorption, metabolism, distribution, and excretion; its behavioral effects; and some of the possible mechanisms of action of quercetin on memory in different animal models. Several important pathways that may be involved in the processes of learning and memory, long-term potentiation, and cognition may be impaired during neurological diseases or other medical conditions. As dietary quercetin is important, provision of its best formulation for delivery to the brain as a nutraceutical and in clinical translational research for the prevention or treatment of Alzheimer's disease and other types of dementia is necessary.

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食物中的槲皮素：其影响记忆的可能机制

槲皮素（3,3',4',5,7-五羟基黄酮）存在于蔬菜和水果中。它是人类饮食中主要的黄酮类化合物之一。槲皮素作为神经保护剂在神经系统中具有多种药理作用。在这篇综述中，我们总结了槲皮素的研究及其在动物和人类记忆中的作用。文章选自 Scopus、PubMed 和 Web of Science 数据库。在这篇综述中，我们描述并总结了槲皮素在体内的重要性，尤其是在大脑中；其动力学，包括其吸收、代谢、分布和排泄；其行为影响；以及槲皮素在不同动物模型中对记忆的一些可能作用机制。可能参与学习和记忆过程的几个重要途径，在神经系统疾病或其他医疗条件下，长期增强和认知可能会受​​损。由于膳食槲皮素很重要，因此必须提供其最佳配方以作为营养药物输送到大脑，并在临床转化研究中用于预防或治疗阿尔茨海默病和其他类型的痴呆症。