Catalysis Communications ( IF 3.4 ) Pub Date : 2018-08-09 , DOI: 10.1016/j.catcom.2018.08.004 Zhiheng Yang , Weiyan Cheng , Zeyun Li
We provide a new transfer hydrogenation of structurally diverse aldehydes and ketones in water using formic acid as hydride donor. The iridium complex of 4,4′,5,5′-tetrahydro-1H,1′H-2,2′-biimidazole, is used as the efficient catalyst. The S/C ratios in aldehyde and ketone reductions are as low as 20,000 and 10,000, respectively. The TOF value in aldehyde reduction is as high as 60,000 h−1. A number of functional groups such as (hetero)aryl, alkenyl, halogen, phenolic and alcoholic hydroxyls, trifluromethyl, cyano, nitro, ester, carboxylic acid, and acidic methylenes are well tolerated.
中文翻译:
铱催化高效转移加氢还原水中的醛和酮
我们使用甲酸作为氢化物供体,提供了水中结构多样的醛和酮的新型转移加氢反应。复杂的4,4铱',5,5'-四氢ħ,1' ħ -2,2'-联咪唑,被用作有效的催化剂。醛和酮还原的S / C比分别低至20,000和10,000。醛还原中的TOF值高达60,000 h -1。很好地耐受许多官能团,例如(杂)芳基,烯基,卤素,酚和醇羟基,三氟甲基,氰基,硝基,酯,羧酸和酸性亚甲基。