Nowadays, the control of pesticide residues in food is well established. The capacity of triple quadrupole technology to satisfy the current food regulations has been demonstrated. However, the permanent high demand of consumers for more sensitive and faster testing is driving the development of improved analytical methodologies that increase the performances of sensitivity and robustness and reduce the analysis time. In this work, the feasibility of decreasing the run time to 12.4 min by modifying the oven temperature program, for a multiresidue method covering 203 pesticides, was evaluated. Satisfactory sensitivity results were achieved by reaching a limit of quantitation of 2 μg kg⁻¹ for a great variety of fruits and vegetables. The validated method based on updated GC-QqQ-MS/MS has confirmed the abovementioned challenges with adequate robustness by its application to routine analyses for 69 real samples. The proposed method can represent great benefit for laboratories as it allows increasing samples throughput. It is also very useful for risk assessment studies, where the needs of low reporting limits and very wide analytical scope are necessary.

如今，食品中农药残留的控制已建立起来。已经证明了三重四极杆技术可以满足当前食品法规的能力。但是，消费者对更高灵敏度和更快测试的永久性高需求正在推动改进分析方法的发展，这些方法可以提高灵敏度和鲁棒性，并减少分析时间。在这项工作中，评估了对于涵盖203种农药的多残留方法，通过修改柱箱温度程序将运行时间减少至12.4分钟的可行性。通过达到2μgkg ^-1的定量限，获得了令人满意的灵敏度结果用于各种各样的水果和蔬菜。经过验证的基于更新的GC-QqQ-MS / MS的方法已通过将其应用于69个真实样品的常规分析中，从而以足够的鲁棒性证实了上述挑战。所提出的方法可以为实验室带来巨大的好处，因为它可以提高样品通量。它对于风险评估研究也非常有用，在该研究中，需要较低的报告限制和非常宽的分析范围。