The extraordinary high pressure and temperature produced during cavitation is crucial for ultrasonic sonochemisty. However, the cavitation effect is usually confined to a small zone nearby the ultrasonic horn, outside of which ultrasound produces much less effects on chemical reaction. In present work, in order to expand the range of effective zone and intensify the cavitation effect, N₂ aeration was introduced to an ultrasonic polymerization process of CuO@PNIPAM in aqueous solution. By increasing the number of bubble nucleus gathered on the CuO surface and lowering the surface tension of the aqueous solution, the cavitation effect is intensified on the CuO surface within the whole reaction vessel, which benefits the covalently bonding of PNIPAM to CuO to a large degree and results in the formation of CuO@PNIPAM hybrid composite with excellent interfacial bonding. It is promising that the hybrid composite can be applied as temperature responsive glucose sensing platform with on and off states due to the wettability change of PNIPAM versus temperature.

空化过程中产生的异常高压和高温对于超声超声化学至关重要。但是，空化作用通常限于超声喇叭附近的一个小区域，在该区域之外，超声对化学反应的影响要小得多。在目前的工作中，为了扩大有效区的范围并增强空化作用，N ₂将曝气引入水溶液中CuO @ PNIPAM的超声聚合工艺中。通过增加聚集在CuO表面上的气泡核的数目并降低水溶液的表面张力，在整个反应容器内的CuO表面上增强了空化作用，这在很大程度上有利于PNIPAM与CuO的共价键合。并形成具有优异界面结合力的CuO @ PNIPAM杂化复合材料。由于PNIPAM相对于温度的可湿性变化，有望将杂化复合材料用作具有开和关状态的温度响应型葡萄糖传感平台。