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Examining the effect of regioisomerism on the physico-chemical properties of lysophosphatidylethanolamine-containing liposomes using fluoro probes
Chemistry and Physics of Lipids ( IF 3.4 ) Pub Date : 2018-08-03 , DOI: 10.1016/j.chemphyslip.2018.08.001
Yusuke Yamamoto , Takayuki Furukawa , Seiji Takeda , Hiroyuki Kashida , Hitoshi Chiba , Shu-Ping Hui

Lysophospholipids (LysoPLs) receive steadily increasing attention in the area of lipid chemistry and biology. However, the physico-chemical properties of individual LysoPL regioisomers have not yet been investigated. Herein, we report the synthesis of fluoro analogues of lysophosphatidylethanolamines (LPEs) and examine the physico-chemical properties of the LPE regioisomers using chemically synthesized fluoro probes.



中文翻译:

使用荧光探针检查区域异构对含溶血磷脂酰乙醇胺的脂质体理化性质的影响

溶血磷脂(LysoPLs)在脂质化学和生物学领域受到越来越多的关注。但是,尚未研究单个LysoPL区域异构体的物理化学性质。在这里,我们报告了溶血磷脂酰乙醇胺(LPEs)的氟类似物的合成,并使用化学合成的氟探针检查了LPE区域异构体的理化性质。

更新日期:2018-08-03
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