Obesity is linked to a chronic low‐grade inflammatory state that contributes to the development of obesity‐associated metabolic disorders. The anti‐inflammatory activities and mechanisms of soyasaponin monomers (A₁, A₂, and I) have been recently demonstrated in cell models. However, their potential in vivo abilities to reduce chronic inflammation and alleviate metabolic disorders in obese status remain unclear.

中文翻译：

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大豆皂甙可减少高脂饮食诱导的肥胖小鼠的炎症并改善其血脂水平和葡萄糖稳态。

肥胖与慢性低度炎症状态有关，慢性炎症状态导致肥胖相关的代谢性疾病的发展。大豆皂素单体（A ₁，A ₂和I）的抗炎活性和机制最近已在细胞模型中得到证实。然而，它们在减轻慢性炎症和减轻肥胖状态下的代谢紊乱方面的潜在体内能力仍不清楚。