In this issue of JAMA Surgery, Jung and colleagues¹ examine the safety and efficacy of venous thromboembolism (VTE) prophylaxis in Korean patients undergoing gastrectomy for cancer. Their randomized clinical trial found decreased postoperative VTE with the use of low-molecular-weight heparin in addition to mechanical prophylaxis, compared with the use of mechanical prophylaxis alone. However, the authors claim that, because the VTE rate was low and the rate of bleeding was increased, VTE prophylaxis (low-molecular-weight heparin plus intermittent pneumatic compression) still may not be the right choice for all patients undergoing gastrectomy. Although we were pleased to see this focus on VTE, which until recently was understudied in Asian patients,² we do have some questions about this trial and its conclusions.

在本期《JAMA Surgery》中，Jung及其同事¹研究了在接受了胃切除术的韩国癌症患者中预防静脉血栓栓塞（VTE）的安全性和有效性。他们的随机临床试验发现，与单纯机械预防相比，除机械预防外，还使用低分子量肝素可降低术后VTE。然而，作者声称，由于VTE率低且出血率增加，因此对于所有接受胃切除术的患者，预防VTE（低分子量肝素加间歇性气压）仍然不是正确的选择。尽管我们很高兴看到对VTE的关注，直到最近对亚洲患者的研究仍很少，² 我们对此试验及其结论确实有一些疑问。