Arbutus unedo fruits, commonly known as strawberry-tree fruits, can be used as raw material for the development of bioactive ingredients, besides other traditional applications. In this work, a high-pressure CO₂ Assisted Extraction process (HPCDAE) was investigated in order to find the best process conditions to obtain extracts with a higher phenolic content (TPC) and antioxidant activity. The process parameters studied were pressure (100, 175 and 250 bar), temperature (40 °C, 55 °C and 70 °C) and volume solid:liquid (S:L)/CO₂ ratios (20, 50 and 80%) and the extracts recovered compared with the extract obtained with a S:L conventional extraction. Results show that when the highest pressure (250 bar) temperature (70 °C) and lowest S:L/CO₂ ratio (20%) are used, HPCDAE increases 1.41 times TPC of the extracts, compared to conventional S-L extract. A significant increase in the extraction of galloyl hexoside and 5-O-galloylquinic acid were observed after HPCDAE application. The intensification of both compounds extraction may be related with the increase in the antioxidant activity of the extracts. The results from this study show that HPCDAE is a promising tool to intensify the extraction of bioactive compounds from strawberry tree fruits.

除其他传统应用外，乌头杨梅果实，通常被称为草莓树果实，可以用作开发生物活性成分的原料。在这项工作中，对高压CO ₂辅助萃取工艺（HPCDAE）进行了研究，以找到最佳工艺条件，以获得具有较高酚含量（TPC）和抗氧化活性的萃取物。研究的工艺参数为压力（100、175和250 bar），温度（40°C，55°C和70°C）和固/液（S：L）/ CO ₂体积比（20％，50％和80％） ），回收的提取物与采用S：L常规提取法得到的提取物相比。结果表明，当最高压力（250 bar）温度（70°C）和最低S：L / CO _2时与传统的SL提取物相比，使用比例（20％）的HPCDAE使提取物的TPC增加1.41倍。施用HPCDAE后，发现没食子酰基己糖苷和5-O-没食子酰基奎宁酸的提取量显着增加。两种化合物提取物的强化作用可能与提取物抗氧化活性的提高有关。这项研究的结果表明，HPCDAE是加强从草莓树果实中提取生物活性化合物的有前途的工具。