Synthesis ( IF 2.2 ) Pub Date : 2018-07-12 , DOI: 10.1055/s-0037-1610415 Sergey Polonik , Yuri Sabutskii , Vladimir Denisenko
Abstract
A series of substituted 2-alkoxy-1,4-naphthoquinone derivatives were obtained by acid-catalyzed condensation of substituted 2-hydroxy-1,4-naphthoquinones with propan-1-ol, butan-1-ol, or pentan-1-ol in good yields. Based on this reaction a versatile preparative synthesis of spinochrome D was developed.
A series of substituted 2-alkoxy-1,4-naphthoquinone derivatives were obtained by acid-catalyzed condensation of substituted 2-hydroxy-1,4-naphthoquinones with propan-1-ol, butan-1-ol, or pentan-1-ol in good yields. Based on this reaction a versatile preparative synthesis of spinochrome D was developed.
中文翻译:
醇对酸取代2-羟基-1,4-萘醌的2-O-烷基化反应:多功能合成Spinochrome D及其6-烷氧基衍生物的合成
摘要
通过将取代的2-羟基-1,4-萘醌与丙-1-醇,丁-1-醇或戊丹-1-酸催化缩合,可获得一系列取代的2-烷氧基-1,4-萘醌衍生物。醇收率高。基于该反应,开发了多用途合成的多色染料D。
通过将取代的2-羟基-1,4-萘醌与丙-1-醇,丁-1-醇或戊丹-1-酸催化缩合,可获得一系列取代的2-烷氧基-1,4-萘醌衍生物。醇收率高。基于该反应,开发了多用途合成的多色染料D。