Gut Microbiota: Acute Oral Administration of Single‐Walled Carbon Nanotubes Increases Intestinal Permeability and Inflammatory Responses: Association with the Changes in Gut Microbiota in Mice (Adv. Healthcare Mater. 13/2018),Advanced Healthcare Materials

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Gut Microbiota: Acute Oral Administration of Single‐Walled Carbon Nanotubes Increases Intestinal Permeability and Inflammatory Responses: Association with the Changes in Gut Microbiota in Mice (Adv. Healthcare Mater. 13/2018)
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2018-07-11 , DOI: 10.1002/adhm.201870053
Hanqing Chen ₁ , Ruifang Zhao ₂ , Bing Wang ₁ , Lingna Zheng ₁ , Hong Ouyang ₁ , Hailong Wang ₁ , Xiaoyan Zhou ₁ , Dan Zhang ₁ , Zhifang Chai ₁ , Yuliang Zhao _{1,

2} , Weiyue Feng ₁

Affiliation

Whether the oral exposure of single‐walled carbon nanotubes (SWCNTs) have an impact on the homeostasis of gut microbiota is an essential step for their safe application. In article 1701313 by Weiyue Feng and co‐workers, the deposited SWCNTs in the intestinal tract disturb intestinal integrity, perform antibacterial activity and drive the compositional alteration in gut microbiota, consequently triggering the “metabolic inflammation” responses.

中文翻译：

肠道菌群：急性口服单壁碳纳米管可增加肠道通透性和炎症反应：与小鼠肠道菌群变化相关（Adv。Healthcare Mater。13/2018）

单壁碳纳米管（SWCNT）的口腔暴露是否会影响肠道菌群的稳态，这是其安全应用必不可少的步骤。在冯卫岳及其同事的文章1701313中，在肠道中沉积的SWCNTs干扰肠道完整性，执行抗菌活性并驱动肠道菌群的组成改变，从而引发“代谢性炎症”反应。

更新日期：2018-07-11

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