当前位置: X-MOL 学术Chem. Commun. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Iodine catalyzed reduction of quinolines under mild reaction conditions†
Chemical Communications ( IF 4.9 ) Pub Date : 2018-07-11 00:00:00 , DOI: 10.1039/c8cc04262d
Chun-Hua Yang 1, 2, 3, 4, 5 , Xixi Chen 1, 2, 3, 4, 5 , Huimin Li 1, 2, 3, 4, 5 , Wenbo Wei 1, 2, 3, 4, 5 , Zhantao Yang 1, 2, 3, 4, 5 , Junbiao Chang 5, 6, 7, 8
Affiliation  

A reduction of quinolines to synthetically versatile tetrahydroquinoline molecules with I2 and HBpin is described. In the presence of iodine (20 mol%) as a catalyst, reduction of quinolines and other N-heteroarenes proceeded readily with hydroboranes as the reducing reagents. The broad functional-group tolerance, good yields and mild reaction conditions imply high practical utility.

中文翻译:

碘在温和的反应条件下催化还原喹啉

描述了用I 2和HBpin将喹啉还原为合成通用的四氢喹啉分子。在碘(20mol%)作为催化剂的存在下,以氢硼烷作为还原剂容易地进行喹啉和其他N-杂芳烃的还原。宽泛的官能团耐受性,良好的收率和温和的反应条件意味着较高的实用性。
更新日期:2018-07-11
down
wechat
bug