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TfOH catalyzed synthesis of 1-substituted tetrahydrocarbazoles
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2018-07-09 , DOI: 10.1016/j.tetlet.2018.07.023
Laxmi Narayan Nanda , Vipin Ashok Rangari

Synthesis of 1-substituted tetrahydrocarbazole is accomplished by TfOH catalyzed reaction of 3-substituted indoles tethered with secondary and tertiary alcohols. The reaction was generalized for a variety of substrates and was extended to the synthesis of 2,3,3a,6-tetrahydro-1H-pyrido[3,2,1-jk]carbazole and carbazoles.



中文翻译:

TfOH催化的1取代四氢咔唑的合成

1-取代的四氢咔唑的合成是通过TfOH催化的与仲和叔醇连接的3-取代的吲哚的反应来完成的。该反应被推广用于多种底物,并扩展到2,3,3a,6-四氢-1 H-吡啶并[3,2,1- jk ]咔唑和咔唑的合成。

更新日期:2018-07-09
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