Front Cover: Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes (ChemBioChem 15/2018),ChemBioChem

当前位置： X-MOL 学术 › ChemBioChem › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Front Cover: Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes (ChemBioChem 15/2018)
ChemBioChem ( IF 2.6 ) Pub Date : 2018-07-09 , DOI: 10.1002/cbic.201800362
Jack G. Ganley ₁ , Gavin Carr ₂ , Thomas R. Ioerger ₃ , James C. Sacchettini ₄ , Jon Clardy ₂ , Emily R. Derbyshire ₁

Affiliation

The front cover picture shows Stephensiolide F, a cycliclipodepsipeptide produced by a Serratia sp. within Anopheles mosquitoes, with the corresponding HMBC NMR spectrum in the background. We determined the structures of eleven stephensiolides with NMR and MS/MS techniques. Stephensiolides were shown to facilitate bacteria swarming motility in addition to having antibiotic and antiparasitic activity. The biosynthetic gene cluster of the stephensiolides was identified, and sequence analysis suggests it is dispersed in Serratia spp. isolated from different ecological niches. More information can be found in the communication by J. Clardy, E. R. Derbyshire, et al. on page 1590 in Issue 15, 2018 (DOI: 10.1002/cbic.201800124).

中文翻译：

封面：发现由沙雷氏菌产生的抗菌脂肽肽。在蚊子微生物群内（ChemBioChem 15/2018）

封面图片显示了由沙雷氏菌（Serratia sp。）生产的环脂二肽StephensiolideF 。在按蚊中具有相应的HMBC NMR光谱。我们用NMR和MS / MS技术确定了11种石竹内酯的结构。除具有抗生素和抗寄生虫活性外，Stephensiolides还显示出促进细菌成群运动的能力。鉴定了stephensiolides的生物合成基因簇，并且序列分析表明其分散在沙雷氏菌中。与不同的生态位隔离。可以在J. Clardy，E。R. Derbyshire等人的来文中找到更多信息。就在第15期，2018页1590 （DOI：10.1002 / cbic.201800124）。

更新日期：2018-07-09

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11