Sensitivity is an important parameter of molecularly imprinted electrochemical sensors, and various methods have been extensively investigated to improve this parameter. This review focuses on recent reports about different methods that can enhance the sensitivity of these sensors. To a great extent, the sensitivity of the molecularly imprinted sensor is limited by the number of cavities formed in a molecularly imprinted polymer on an electrode after elution. To enhance sensitivity and fabricate sensing devices, researchers employ signal amplification by labels, amplification by functional materials doped in imprinted membranes, sensitive film amplification, and other methods. Some perspectives in this research area, current problems, and challenges are also outlined.

灵敏度是分子印迹电化学传感器的重要参数，并且已经广泛研究了各种方法来改善该参数。这篇评论集中在有关可以提高这些传感器的灵敏度的不同方法的最新报告上。在很大程度上，分子印迹传感器的灵敏度受到洗脱后在电极上的分子印迹聚合物中形成的空穴数量的限制。为了提高灵敏度并制造传感设备，研究人员采用了通过标签进行信号放大，通过印迹膜中掺杂的功能材料进行放大，敏感膜放大以及其他方法。还概述了该研究领域中的一些观点，当前的问题和挑战。