Chlorinated paraffins (CPs) are high production volume chemicals. Their analysis is demanding and becomes even more challenging in presence of CP transformation products. Chlorinated olefins (COs) are expected thermal CP transformation products that are present in technical CP products and in the environment. Thus, a specific analysis of CPs and COs is important. Commonly, CPs are analysed by gas chromatography electron capture negative ionisation mass spectrometry (GC-ECNI-MS). It was shown that GC-ECNI-MS suffers from in-source formation of COs. Further, selected ion monitoring can lead to false quantification of COs as CPs. Alternative methods based on liquid chromatography and soft ionisation techniques can solve the CP/CO problem. Non-interfered CP data is inevitable for CP transformation studies and non-biased degradation kinetics. Data about CP transformation is urgently needed, but respective studies are challenging. In here, we provided an analytical guide to deal with severe mass interferences of CPs and their transformation products.

氯化石蜡（CPs）是高产量的化学品。他们的分析是苛刻的，并且在CP转换产品的存在下变得更具挑战性。氯化烯烃（CO）是预期的热CP转化产品，存在于工业CP产品和环境中。因此，对CP和CO进行特定分析非常重要。通常，通过气相色谱电子捕获负电离质谱（GC-ECNI-MS）分析CP。结果表明，GC-ECNI-MS遭受源内生成CO的困扰。此外，选择的离子监测可能导致错误量化COs作为CP。基于液相色谱和软电离技术的替代方法可以解决CP / CO问题。对于CP转化研究和无偏降解动力学，不可避免的CP数据是不可避免的。迫切需要有关CP转换的数据，但是各自的研究具有挑战性。在这里，我们提供了分析指南，以处理CP及其转换产物的严重质量干扰。