Comprehensive two-dimensional gas chromatography (GC×GC) and multidimensional GC (MDGC) offer high performance separation capability towards multi-component samples, and improved sample characterisation. Recent advances, particularly with new GC×GC methodologies, which apply additional columns to GC×GC, along with hyphenation with mass spectrometry, potentially have a tremendous impact on the analysis of various applications such as food, petrochemicals, fragrances, drugs and environmental samples. The present review highlights the new experimental designs in GC×GC coupled with MDGC to offer significant changes in operational performance, and applications of these technologies which have been developed since 2000.

全面的二维气相色谱（GC×GC）和多维气相色谱（MDGC）为多组分样品提供了高性能的分离能力，并改善了样品的表征。最近的进展，特别是采用新的GC×GC方法学的技术，将新的色谱柱应用于GC×GC以及质谱联用技术，可能对食品，石化产品，香料，药物和环境样品等各种应用的分析产生巨大影响。本综述着重介绍了GC×GC与MDGC结合使用的新实验设计，以提供运行性能的重大变化，以及自2000年以来开发的这些技术的应用。