A novel palladium-catalyzed C-H formylation of electron-rich N-, O-, and S-containing heteroarenes has been developed. The key to success is that the commercially available BrCHCl₂ was used as a stoichiometric carbonyl source. Mechanistic investigations indicated that different from the known Reimer-Tiemann reaction, this net C-H formylation proceeded through an electrophilc radical-type path.

中文翻译：

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钯催化的自由基二氯甲基化富电子杂芳烃的CH甲酰化

已经开发了新型的钯催化的富电子的N，O和S杂芳烃的CH甲酰化反应。成功的关键是将市售的BrCHCl ₂用作化学计量的羰基来源。机理研究表明，与已知的Reimer-Tiemann反应不同，这种净的CH甲酰化反应是通过亲电子自由基类型的路径进行的。