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Direct synthesis of N-arylamides via the coupling of aryl diazonium tetrafluoroborates and nitriles under transition-metal-free conditions
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2018-07-04 , DOI: 10.1016/j.tetlet.2018.07.014
Biquan Xiong , Gang Wang , Tao Xiong , Liming Wan , Congshan Zhou , Yu Liu , Panliang Zhang , Changan Yang , Kewen Tang

The direct synthesis of N-arylamides via the coupling of aryl diazonium tetrafluoroborates and nitriles under transition-metal-free conditions has been developed. The reported protocol is practical and represents an efficient method to produce functionalized amides in moderate to good yields.



中文翻译:

在无过渡金属的条件下通过芳基重氮四氟硼酸酯与腈的偶合直接合成N-芳基酰胺

已经开发了在无过渡金属的条件下通过芳基重氮四氟硼酸酯和腈的偶联直接合成N-芳基酰胺的方法。所报道的方案是实用的,并且代表了以中等至良好的产率生产官能化酰胺的有效方法。

更新日期:2018-07-04
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