Chaotic printing: using chaos to fabricate densely packed micro- and nanostructures at high resolution and speed†,Materials Horizons

当前位置： X-MOL 学术 › Mater. Horiz. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Chaotic printing: using chaos to fabricate densely packed micro- and nanostructures at high resolution and speed†
Materials Horizons ( IF 12.2 ) Pub Date : 2018-07-03 00:00:00 , DOI: 10.1039/c8mh00344k
Grissel Trujillo-de Santiago _{1,

2,

3,

4} , Mario Moisés Alvarez _{1,

2,

3,

4} , Mohamadmahdi Samandari _{1,

2,

5} , Gyan Prakash _{1,

2} , Gouri Chandrabhatla _{1,

2} , Pamela Inés Rellstab-Sánchez _{1,

2,

4} , Batzaya Byambaa _{1,

2} , Parisa Pour Shahid Saeed Abadi _{1,

2} , Serena Mandla _{1,

2,

6} , Reginald K Avery _{1,

2,

7} , Alejandro Vallejo-Arroyo _{1,

2,

4} , Amir Nasajpour _{1,

2,

8,

9} , Nasim Annabi _{1,

2,

8,

10} , Yu Shrike Zhang _{1,

2} , Ali Khademhosseini _{1,

2,

6,

8,

9,

11,

12,

13,

14}

Affiliation

Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge 02139, MA, USA.
Harvard-MIT Division of Health Sciences and Technology, Cambridge 02139, MA, USA.
Microsystems Technologies Laboratories, MIT, Cambridge, 02139, MA, USA.
Centro de Biotecnología-FEMSA. Escuela de Ingeniería y Ciencias, Tecnologico de Monterrey, Monterrey, 64849, Nuevo León, Mexico.
School of Mechanical Engineering, College of Engineering, University of Tehran, Tehran 11155-4563, Iran.
Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston 02115, MA, USA.
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, 02139, MA, USA.
Department of Bioengineering, Department of Chemical and Biomolecular Engineering, Henry Samueli School of Engineering and Applied Sciences, University of California-Los Angeles, Los Angeles, CA, USA.
California NanoSystems Institute (CNSI), University of California-Los Angeles, Los Angeles, CA, USA.
Department of Chemical Engineering, Northeastern University, Boston, 02115-5000, MA, USA.
Center for Nanotechnology, King Abdulaziz University, Jeddah 21569, Saudi Arabia.
KU Convergence Science and Technology Institute, Department of Bioindustrial Technologies, College of Animal Bioscience and Technology, Konkuk University, Seoul 05029, Republic of Korea.
Department of Radiology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA.
Center for Minimally Invasive Therapeutics (C-MIT), University of California-Los Angeles, Los Angeles, CA, USA.

Nature generates densely packed micro- and nanostructures to enable key functionalities in cells, tissues, and other materials. Current fabrication techniques, due to limitations in resolution and speed, are far less effective at creating microstructures. Yet, the development of extensive amounts of surface area per unit volume will enable applications and manufacturing strategies not possible today. Here, we introduce chaotic printing—the use of chaotic flows for the rapid generation of complex, high-resolution microstructures. A simple and deterministic chaotic flow is induced in a viscous liquid, and its repeated stretching and folding action deforms an “ink” (i.e., a drop of a miscible liquid, fluorescent beads, or cells) at an exponential rate to render a densely packed lamellar microstructure that is then preserved by curing or photocrosslinking. This exponentially fast creation of fine microstructures exceeds the limits of resolution and speed of the currently available 3D printing techniques. Moreover, we show that the architecture of the microstructure to be created with chaotic printing can be predicted by mathematical modelling. We envision diverse applications for this technology, including the development of densely packed catalytic surfaces and highly complex multi-lamellar and multi-component tissue-like structures for biomedical and electronics applications.

中文翻译：

混沌打印：利用混沌以高分辨率和速度制造密集的微米和纳米结构†

大自然会产生密集的微米和纳米结构，以实现细胞、组织和其他材料的关键功能。由于分辨率和速度的限制，当前的制造技术在创建微结构方面的效率要低得多。然而，每单位体积的大量表面积的发展将使当今不可能的应用和制造策略成为可能。在这里，我们介绍混沌打印——利用混沌流快速生成复杂、高分辨率的微观结构。在粘性液体中引发简单且确定性的混沌流，其重复的拉伸和折叠动作使“墨水”（即一滴可混溶液体、荧光珠或细胞）以指数速率变形，从而呈现出紧密堆积的状态。然后通过固化或光交联保留层状微结构。这种精细微结构的快速创建超出了当前可用 3D 打印技术的分辨率和速度限制。此外，我们还表明，可以通过数学建模来预测用混沌打印创建的微结构的架构。我们设想这项技术的多种应用，包括开发用于生物医学和电子应用的致密催化表面和高度复杂的多层和多组分组织状结构。

更新日期：2018-07-03

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11