Kinetically Stable Bicelles with Dilution Tolerance, Size Tunability, and Thermoresponsiveness for Drug Delivery Applications,ChemBioChem

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Kinetically Stable Bicelles with Dilution Tolerance, Size Tunability, and Thermoresponsiveness for Drug Delivery Applications
ChemBioChem ( IF 2.6 ) Pub Date : 2018-08-10 , DOI: 10.1002/cbic.201800304
Noriyuki Uchida ₁ , Noriko Nishizawa Horimoto ₁ , Kuniyo Yamada ₁ , Takaaki Hikima ₂ , Yasuhiro Ishida ₁

Affiliation

Frozen membrane disks: Bicelles with structures that are kinetically frozen at room temperature were developed by assembling a phospholipid with a high bilayer melting point and a surfactant with an exceptionally low critical micelle concentration. The bicelles showed kinetic stability, dilution tolerance, size tunability, and thermoresponsiveness that could be useful in transdermal drug delivery.

中文翻译：

具有动力学稳定性的Bicelles，具有稀释耐受性，尺寸可调性和热响应性，适用于药物输送应用

冷冻膜盘：通过组装具有高双层熔点的磷脂和具有极低临界胶束浓度的表面活性剂，开发出具有在室温下动态冷冻的结构的Bicell。Bicells显示出动力学稳定性，稀释耐受性，尺寸可调性和热响应性，可用于透皮给药。

更新日期：2018-08-10

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