Catalytic glycosylation has been a central reaction in carbohydrate chemistry since its introduction by Fischer 125 years ago, but it is only in the past three to four decades that catalytic methods for synthesizing oligosaccharides have appeared. Despite the development of numerous elegant and ingenious catalytic glycosylation methods, only a few are in general use. This review covers all methods of catalytic glycosylation with the focus on the development and application in oligosaccharide synthesis and provide an overview of the scope and limitations of these. The review also includes relevant mechanistic studies of catalytic glycosylations. The future of catalytic glycosylation chemistry is discussed, including specific, upcoming methods and possible directions for the field of research in general.

中文翻译：

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寡糖合成中的催化糖基化

自125年前由Fischer引入以来，催化糖基化一直是碳水化合物化学中的中心反应，但直到最近三到四十年，才出现了合成寡糖的催化方法。尽管开发了许多优雅而巧妙的催化糖基化方法，但只有少数几种是普遍使用的。这篇综述涵盖了催化糖基化的所有方法，重点是寡糖合成的开发和应用，并概述了这些方法的范围和局限性。该评价还包括催化糖基化的相关机理研究。讨论了催化糖基化化学的未来，包括特定的，即将到来的方法以及一般研究领域的可能方向。