A gold-catalyzed post-Ugi ipso-cyclization for the diastereoselective synthesis of spirocyclic pyrrol-2-one-dienone system is described. Tuning the catalytic system, solvent, and temperature allowed selectively attaining two sets of diastereoisomers. The scope of the process has been evaluated, and a putative mechanistic model was proposed.

中文翻译：

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具有可转换的非对映选择性的金催化的Ugi益普索后环化

描述了一种金催化的Ugi ipso环化，用于非对映选择性合成螺环吡咯-2-酮-二烯酮系统。调整催化体系，溶剂和温度可以选择性地获得两组非对映异构体。已经评估了该过程的范围，并提出了一个假定的机械模型。