Fluorinase‐catalysed radiosynthesis for PET: New amine‐ and acid‐functionalised fluorinase substrates can be attached to an extensive range of carboxylate‐ or amine‐containing bioactive molecules prior to their enzymatic radiolabelling with [¹⁸F]fluoride. Two new substrates of this class have been applied in a pretargeting approach for radiolabelling of conjugated antibodies and proteins for PET imaging.

中文翻译：

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生物素和四嗪共轭物的酶促氟化反应用于正电子发射断层显像成像的预靶向方法

氟化酶催化的PET放射合成：在用[ ¹⁸ F]氟化物进行放射性标记之前，可以将新的胺和酸官能化的氟化酶底物连接到多种含羧酸盐或胺的生物活性分子上。此类的两种新底物已用于预靶向方法中，以放射性标记用于PET成像的结合抗体和蛋白质。