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Novel Self-assembled Organic Nanoprobe for Molecular Imaging and Treatment of Gram-positive Bacterial Infection
Theranostics ( IF 12.4 ) Pub Date : 2018-02-14 , DOI: 10.7150/thno.22534
Tang Gao 1 , Hongliang Zeng 2 , Huan Xu 3 , Feng Gao 3 , Wei Li 3 , Shengwang Zhang 3 , Yi Liu 1 , Guifang Luo 2 , Mingdan Li 2 , Dejian Jiang 2 , Zhigao Chen 2 , Yong Wu 3 , Wei Wang 3 , Wenbin Zeng 1
Affiliation  

Background: Increasing bacterial infections as well as a rise in bacterial resistance call for the development of novel and safe antimicrobial agents without inducing bacterial resistance. Nanoparticles (NPs) present some advantages in treating bacterial infections and provide an alternative strategy to discover new antibiotics. Here, we report the development of novel self-assembled fluorescent organic nanoparticles (FONs) with excellent antibacterial efficacy and good biocompatibility.

中文翻译:


用于分子成像和治疗革兰氏阳性细菌感染的新型自组装有机纳米探针



背景:细菌感染的增加以及细菌耐药性的增加,需要开发新型且安全的抗菌剂,而不引起细菌耐药性。纳米颗粒(NP)在治疗细菌感染方面具有一些优势,并为发现新抗生素提供了一种替代策略。在此,我们报告了新型自组装荧光有机纳米粒子( FON )的开发,其具有优异的抗菌功效和良好的生物相容性。
更新日期:2018-07-01
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