Rationale: Cardenolides have potential as anticancer drugs. 3′-epi-12β-hydroxyfroside (HyFS) is a new cardenolide structure isolated by our research group, but its molecular mechanisms remain poorly understood. This study investigates the relationship between its antitumor activities and autophagy in lung cancer cells.

中文翻译：

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3'-epi-12β-羟基糖苷（一种新的烯醇内酯）通过阻断肺癌细胞中的Hsp90 / Akt / mTOR轴诱导细胞保护性自噬

理由：胡萝卜素具有作为抗癌药的潜力。3'-epi-12β-羟基糖苷（HyFS）是我们研究小组分离出的一种新的烯醇内酯结构，但其分子机制仍知之甚少。这项研究调查了其抗肿瘤活性与肺癌细胞自噬之间的关系。