In order to better understand the relationships among current Nostocales cyanobacterial blooms, eight genomes were sequenced from cultured isolates or from environmental metagenomes of recent planktonic Nostocales blooms. Phylogenomic analysis of publicly available sequences placed the new genomes among a group of 15 genomes from four continents in a distinct ADA clade (Anabaena/Dolichospermum/Aphanizomenon) within the Nostocales. This clade contains four species-level groups, two of which include members with both Anabaena-like and Aphanizomenon flos-aquae-like morphology. The genomes contain many repetitive genetic elements and a sizable pangenome, in which ABC-type transporters are highly represented. Alongside common core genes for photosynthesis, the differentiation of N₂-fixing heterocysts, and the uptake and incorporation of the major nutrients P, N and S, we identified several gene pathways in the pangenome that may contribute to niche partitioning. Genes for problematic secondary metabolites—cyanotoxins and taste-and-odor compounds—were sporadically present, as were other polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) gene clusters. By contrast, genes predicted to encode the ribosomally generated bacteriocin peptides were found in all genomes.

为了更好地了解当前的诺氏藻蓝藻水华之间的关系，从培养的分离物或最近浮游的诺氏藻水华的环境元基因组中测序了八个基因组。对可公开获得的序列进行系统生物学分析，将新的基因组放置在来自四个大洲的15个基因组中的一组中，这些基因组位于诺斯托卡利斯的一个不同的ADA分支（鱼腥藻/茄子/ Aphanizomenon）中。该进化枝包含四个物种级别的群体，其中两个群体既有类似鱼腥藻的成员，也有同属异色藻的成员。形态。基因组包含许多重复的遗传元件和相当大的泛基因组，其中高度代表ABC型转运蛋白。除了光合作用的常见核心基因，固定N _2的异质囊的分化以及主要养分P，N和S的吸收和掺入外，我们还确定了全基因组中可能有助于生态位分配的几种基因途径。与其他聚酮化合物合酶（PKS）和非核糖体肽合成酶（NRPS）基因簇一样，偶发地存在有问题的次级代谢产物的基因-氰毒素和味觉与气味的化合物。相反，在所有基因组中都发现了预测编码核糖体产生的细菌素肽的基因。