In physiological conditions, the response to oxidative stress induced by strenuous physical training, is not always efficient. Furthermore, a weak muscle fiber antioxidant system can contribute to muscle wasting during ageing and pathological conditions. Natural antioxidant supplements could counteract the effects of oxidative stress. An in vitro model of exercise allowed us to mimic intense or moderate exercise by electrically stimulating cultured mouse myotubes with high- and/or low-frequency pulses; the resulting ROS production was then monitored. The herbal supplement Rhodiola rosea aqueous extract was characterized in terms of its polyphenol content and used to test for antioxidant activity against ROS, produced during muscle contraction. Our results showed that Rhodiola rosea extract reduced the oxidative stress produced by muscle contraction and brought values of ROS production back to physiological levels. We suggest that Rhodiola rosea root extract could exert a protective antioxidant role during intense physical exercise.

在生理条件下，对剧烈体育锻炼引起的氧化应激的反应并不总是有效的。此外，弱的肌纤维抗氧化剂系统会导致衰老和病理状况下的肌肉消瘦。天然抗氧化剂补充剂可以抵消氧化应激的影响。的体外运动模型使我们能够模仿强烈或适度的运动通过电刺激与高和/或低频率脉冲培养的小鼠肌管中; 然后监测所产生的ROS产生。草药补品红景天水提取物的特征在于其多酚含量，可用于测试肌肉收缩过程中产生的针对ROS的抗氧化活性。我们的结果表明玫瑰红景天提取物减少了肌肉收缩产生的氧化应激，并使ROS的产生值恢复到生理水平。我们建议玫瑰红景天根提取物可以在激烈的体育锻炼中发挥保护性的抗氧化作用。