Background

Phenolic compounds (PC) have received much attention due to their potential bioactive and functional properties. The common solvents used to extract PC from natural sources are organic solvents, which may contribute to environmental pollution and cause health problems in persons. The advent of green chemistry is forcing scientists to explore greener solvents. Recently, cyclodextrins (CDs) in aqueous solution have been applied as extraction solvents for PC.

Scope and approach

The extraction role of CDs is mainly attributed to their capacity to form inclusion complexes with PC. This review provides an overview of the key factors involved in the extraction process: type of CD, CD concentration, extraction temperature and time, and extraction technique. Advantages of the CD-assisted extraction of PC are summarized and future research needs are also proposed.

Key findings and conclusions

The addition of CD to the water improves the extraction efficiency for PC and shortens the extraction time, and the obtained PC extract present better antioxidant activity. Not only is the removal of CD unnecessary, but also the presence of CD favors the preparation of the PC extract in a solid state, which are very beneficial since they will be expected to be used either to fortify foods or as a food supplement on an industrial scale. However, further studies are required to evaluate the possibility of combining CDs with other extraction methods, such as high hydrostatic pressure, pulsed electric fields, negative pressure cavitation and pressurized liquid extraction, to extract PC from natural materials.

中文翻译：

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环糊精辅助提取酚类化合物的研究现状与展望

背景

酚类化合物（PC）由于其潜在的生物活性和功能特性而备受关注。用于从天然来源提取PC的常用溶剂是有机溶剂，这可能会造成环境污染并引起人体健康问题。绿色化学的到来迫使科学家们探索更绿色的溶剂。最近，水溶液中的环糊精（CD）已被用作PC的提取溶剂。

范围和方法

CD的提取作用主要归因于它们与PC形成包合物的能力。这篇综述概述了提取过程中涉及的关键因素：CD的类型，CD浓度，提取温度和时间以及提取技术。总结了CD辅助提取PC的优点，并提出了未来的研究需求。

主要发现和结论

向水中添加CD可以提高PC的提取效率并缩短提取时间，并且所得PC提取物具有更好的抗氧化活性。不仅没有必要除去CD，而且CD的存在有利于制备固态PC提取物，这是非常有益的，因为可以预期它们将被用于强化食品或用作食品添加剂。工业规模。但是，需要进一步的研究来评估将CD与其他提取方法（例如高静水压力，脉冲电场，负压空化和加压液体提取）组合以从天然材料中提取PC的可能性。