The first example of the palladium catalysed amidotelomerisation is presented, in style of the ambitious carboxytelomerisation. A straightforward synthetic tool was generated to produce several industrial relevant pelargonic C₉-amides based on the fundamental chemical feedstocks: 1,3-butadiene, carbon monoxide and secondary amines. The reaction network was uncovered and crucial influences were determined by design of experiments (DoE). Through the incorporation of an auto-tandem palladium acetate/diphenylphosphino ethane catalytic system, very good yields up to 77% of the desired amides and excellent selectivities of carbonylation products of 94% were achieved. The application of the amidotelomerisation conditions to different classes of amines offered a broad range of the corresponding pelargonic C₉-amides. Understanding the tandem catalysis, significant inhibition factors were uncovered and through a stepwise optimisation, for the first time a carbonylation reaction of octadienyl amines (telomer products) was shown, yielding in 99% of the desired linear pelargonic C₉-amide.

以雄心勃勃的羧基端粒化的形式，提出了钯催化的酰胺基端粒化的第一个例子。产生了一种简单的合成工具，可以基于基本的化学原料生产几种工业相关的壬基碳₉酰胺：1，3-丁二烯，一氧化碳和仲胺。发现了反应网络，并通过实验设计（DoE）确定了关键影响。通过合并汽车-串联的乙酸钯/二苯基膦乙烷乙烷催化体系，获得了高达77％所需酰胺的非常高的收率，以及94％的优异羰基化产物选择性。将酰胺基端粒化条件应用于不同种类的胺提供了广泛的相应的壬基C _9-酰胺。了解串联催化后，发现了显着的抑制因子，并通过逐步优化，首次显示了辛二烯基胺（端粒产物）的羰基化反应，可制得99％的所需线性pelargonic C _9-酰胺。